Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Biofortuna to Provide HLA Kits for Lab901's PCR-Based Diagnostic Platform
Lab901 will optimize its ScreenTape PCR diagnostics platform for use with Biofortuna’s multiplex PCR diagnostics kits for the detection of celiac disease and other HLA-related disease such as reactive arthritis, diabetes, and drug hypersensitivity.
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