Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Agilent Acquires MassCode IP for Multiplex PCR, Plans to Commercialize Infectious Disease Panels
The company is currently collaborating with Ian Lipkin's lab at Columbia University to co-develop a set of MassTag PCR panels for infectious disease screening that it plans to commercialize some time in the next year.
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