Sponsor: Rubicon Genomics
Recording Date: 2/19/2014
Recording Time: 1 hour
Fred Hutchinson Cancer Research Center, home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation, the Center's five scientific divisions collaborate to form a unique environment for conducting basic and applied science.
The Hutchinson Center, in collaboration with its clinical and research partners, the University of Washington and Seattle Children's, is the only National Cancer Institute-designated comprehensive cancer center in the Pacific Northwest. Join us and make a difference!
The dynamic interplay between a pathogen and a host's immune system forms a remarkable evolutionary process. When the pathogen under study is a virus that evolves rapidly within the host over the course of a chronic infection, evolution can be observed as it proceeds in real time through genetic sequencing of both sides of the conflict. Binding and neutralization ability can be tested by growing virus in culture and transfecting antibody sequences into B cells.
A greater understanding of the co-evolution of pathogens and the immune system will lead to improved vaccines for infectious disease, as well as have significant consequences for cancer immunotherapy.
We have an opening for a postdoc to come develop and apply methods to learn from rapidly evolving viruses and antibody-making B cells via their molecular sequences. We would like someone who is strong in computational statistics and/or molecular evolution, but who is motivated by and very engaged with the underlying biology. This project will involve significant computer programming and data analysis, but no wet lab work. The work will be collaborative with Trevor Bedford, Vladimir Minin, and Harlan Robins as well as many lab-based collaborators including Julie Overbaugh.
This position will come with a competitive postdoc-level salary with great benefits for a two-year position with some possibility of extension. Fred Hutchinson Cancer Research Center, home of about 190 faculty including three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research. The environment is lively yet casual, with a strong emphasis on collaborative work.
The Center is housed in a lovely campus next to Lake Union a short walk from downtown, and a slightly longer walk from the University of Washington. Powerful computing resources and a helpful IT staff await you.
If you are interested in this position, please submit representative publications, code samples, and a CV.
- Ph.D. in computer science, math, physics, or another computation-heavy discipline
- Solid foundation in machine learning algorithms
- Linux and computer programming proficiency
- Clear ability for independent research
To apply for this position, please CLICK HERE