Research Bioinformatician I

Organization: 
Cedars-Sinai Medical Center
Job Location: 
Los Angeles
Job Description: 

Summary of Essential Job Duties:

Under some supervision, the Research Bioinformatician I performs general bioinformatics analysis and software support for genomics projects. The RBI will manage genomics data including loading and querying data from database system and public repositories and transform and merge multi-level genomic data into user-friendly formats, assist in development, test and maintenance of modular software pipelines, provide daily bioinformatics data analysis, preliminary interpretation of the data, and reports of the results for possible publications.

Specifically, you will be working in the Genomics core as part of an integrated team of wet lab and informatic scientists. Your main responsibility will be to manipulate large datasets from whole genome type scans, perform tests to determine biological significance, and visualize biologically meaningful data. This is a very dynamic position for instance, where you will use a variety of basic analysis tools to determine things like genetic linkage, gene expression profiles, and molecular classifiers from data generated from microarrays, qPCR data, and Next Gen Sequencing.

You will assist in specific advanced collaborations with the Core Directors collaborative lead research as well as help to translate developmental pipelines for filtering and analyzing these large datasets.

Summarizes data analyses results in the form suitable as the basis for the first draft of written reports, and makes preliminary interpretations of the data.

Manages data including loading and querying data from database systems, downloading genomic data from public repositories, and transforming data to the necessary formats.

Helps to identify, evaluate, and incorporate relevant algorithms and software pipelines by reviewing pertinent literatures in bioinformatics and computational biology.

Requirements: 


Qualification Requirements/Preferences:

Education Certifications/Licensure Experience Physical Abilities Educational Requirements:
Master’s degree in Biostatistics, Statistics, Bioinformatics, Genetics or related field of molecular biology. PhD preferred.
Must have proven expertise in biostatistics, large-scale computing, biological data, and bioinformatics.

Experience:
• Five (5) years of experience (masters level) or 0-1 years Ph.D. level directly related to bioinformatics in genomics (i.e. genomics, transcriptomics, epigenomics, resequencing analysis, etc.). Must have experience in managing the development and deployment of systems that will be used for full Integrated genomic analysis.
• Must have expertise in correlating molecular and clinical measures, and in applying algorithms for clustering and classifying samples by molecular measures.
• Must have R, Bioconductor, Perl, Python, Unix/Linux, SGE Programming knowlege.
• Must have outstanding oral and written communication skills.
• Must have the ability to completely define an analytical approach for defined scientific questions.
• Must successfully interact with outside customers and/or functional peer groups.
• Ability to manage multiple assignments.
• Strong ability to act in a consultative manner with investigators on data analysis; and be able to work independently, manage priorities, and accurately produce results in a timely manner.
• Leads in the development of analytical pipelines for biological data. Leads in the development of innovative data analysis capabilities.
• Publishes collaborative research and gives presentations at meetings of biological, bioinformatic, or other professional groups, thereby reporting results of bioinformatic/biomedical research.
• Prepares bioinformatics reports, manuscripts, and bioinformatics sections of grant applications.
• Coordinates bio-analysis with scientists, bioinformatists, computer administrators, and wetlab staff.
• Devises or develops new biological methods and techniques. Assists in validation of methods.
• Completes other duties as assigned.

Physical Demands:
• Ability to sit for moderate periods of time.
• Ability to use a computer workstation for moderate periods of time.
• Ability to walk and be on one’s feet for moderate periods of time.

Contact Information: 


Please send CV to "genomics at csmc.edu" and apply on line at cedars (http://www.cedars-sinai.edu/Careers/)