Computational Biology, Bioinformatics, Systems Biology (MGH, Harvard Medical School)

MGH & Harvard Medical School
Job Location: 
Boston, Massachusetts, USA
Job Description: 

Applications are invited for a post-doctoral position in Computational and integrative Systems biology in the Ng Lab at Massachusetts General Hospital (MGH) and Harvard Medical School (

The lab is situated in a vibrant and highly collaborative multi-disciplinary research environment within the Center for the Study of Inflammatory Bowel Disease (CSIBD) ( at the MGH which is currently ranked as one of the nation’s top hospitals. This lab benefits from close collaborations on both computational and experimental fronts within the CSIBD and state-of-the-art high-throughput screening and computational platforms at the Broad Institute of MIT & Harvard. Our lab utilizes integrative systems approaches involving computation and high-throughput experimentation (RNA interference (RNAi) and chemical biology screens, transcriptomics, proteomics, metabolomics, and data from genome-wide association studies (GWAS)).

We are seeking creative and highly motivated applicants who have a strong interest in ‘Big Data’ analytics in the Biomedical sciences, and in pursuing computational and systems-level research into understanding microbial sensing, biological circuits, networks and pathways in regulating immune responses to microbes or their dysregulation in complex human genetic diseases and inflammatory disorders, including Crohn’s disease and ulcerative colitis. This position also provides opportunities to participate in exciting multi-disciplinary research programs investigating the interplay of host genetics and environmental factors in influencing immune responses and disease outcomes.


Applicants should have a Ph.D., with a quantitative background in one or more of the following:
Computational biology, Computer science/Machine learning/Data-mining, Statistics, Mathematics or Physics.

Programming proficiency in Java/C, Python/Perl, and MATLAB/R is required. Additionally, experience in Next-Generation sequencing (NGS)/RNA-seq analysis, and genome-wide epigenetic profiling, as evidenced by scientific publications in peer-reviewed journals, would be a plus. Excellent written and verbal communication skills are essential.

Contact Information: 

Interested applicants should email your CV with contact information of three referees, and a cover letter outlining your career goals. (Email: