Fred Hutchinson Cancer Research Center, home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation, the Center's five scientific divisions collaborate to form a unique environment for conducting basic and applied science. The Hutchinson Center, in collaboration with its clinical and research partners, the University of Washington and Seattle Children's, is the only National Cancer Institute-designated comprehensive cancer center in the Pacific Northwest. Join us and make a difference!
The post-doctoral research fellow will work on independent and collaborative projects developing adoptive T cell immunotherapy for hematologic malignancies within the Program in Immunology and Clinical Research Division at FHCRC. The successful applicant will employ strategies for genetic modification of human T cells to enable their expression of chimeric antigen receptors (CARs) and redirection of specificity to antigens expressed by hematologic malignancies.
In vitro studies using human T cells and in vivo xenogeneic models will be used to develop and test novel T cell therapies that can be studied in future human clinical trials. The Program in Immunology is a leader in the development and clinical application of adoptive immunotherapy using genetically modified T cells and is committed to the advancement of this approach.
Applicants will have a PhD in a biological science and/or a MD. The ideal candidate will have a research background in immunology with robust skills in molecular and cellular biology, including lentiviral vector design and cloning, virus production, cell culture, flow cytometry, ELISPOT, and T cell cytotoxicity assays. To be successful in this position, the post-doctoral research fellow must be highly motivated to establish a career as a future independent investigator.
This is a full-time position with a salary based on the NIH scale and excellent benefits.
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