Neurodegeneration Associate Scientist

Novartis Pharmaceuticals
Job Location: 
Cambridge, MA
Job Description: 

About Novartis Institutes for Biomedical Research

At Novartis Institutes for BioMedical Research (NIBR), the global research organization of Novartis, we are committed to discovering innovative medicines to cure disease and improve human health. By hiring the best academic, biotech, and pharmaceutical trained scientists, we have fostered an atmosphere for drug discovery where innovation is rewarded. It is ultimately the talent of the individual that determines our success, while our state-of-the-art technologies and resources enable these ideas to be realized.

NIBR has sites in Cambridge, Massachusetts; Emeryville, CA; Basel, Switzerland; Horsham, UK; and Shanghai, China. Our Cambridge, MA, location is the global research headquarters and has focuses in areas including Pathway Biology, Oncology, Ophthalmology, Metabolism, Muscle, Epigenetics, Neuroscience and Regenerative Medicine. It has a variety of positions in Biology, Chemistry, Biologics, Protein Sciences, and other technologies and additionally in functions such as Patents, Computational Resources, Alliance Management, Operations and other areas that support our scientific resources.

About Neuroscience in Cambridge, Massachusetts

The newly established Neuroscience Department being built in Cambridge, MA will leverage the recent expansion in human genetics and brain circuitry data to develop therapeutics in neuropsychiatric disease including Autism, Schizophrenia, and Epilepsy, and in neurodegenerative diseases including Alzheimer?s, ALS/FTD, and Parkinson?s. Advanced technologies such as induced pluripotent stem cells (iPS), next generation sequencing, and computational biology will be used to discover new targets and drive projects to the clinic.

Job Description / Key Responsibilities

We are seeking an experienced research associate to join our new Neurosciences group in Cambridge, MA. You will assume a hands-on role in a team responsible for research in neurodegenerative disorders, including Frontal Temporal Dementia (FTD) and Alzheimer's disease. You will conceive, conduct, and analyze experiments to evaluate compounds or biologics in cell-based and in vivo disease models. These include, but are not limited to, primary neuronal and glial cell culture, human ES/iPS derived neurons, brains and biological fluids from animal models. As part of the team, you will work closely with other Novartis groups and programs to develop disease area expertise, validate targets, and advance significant findings for drug development.

Qualified candidates will have a BS or MS in Biochemistry, Molecular Biology, Neurobiology or a related field with 3+ years of relevant laboratory experience. Proficiency in the use of current biochemistry, molecular and cell biology techniques is essential, as well as extensive experience in mammalian cell culture methods, cellular and biochemical assay development. Candidates must be highly motivated, team oriented, and have excellent communication and interpersonal skills.

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. Our policies are not to discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.