The Virginia Bioinformatics Institute (VBI) at Virginia Tech performs world-class informatics research in life sciences, social sciences, and human health by integrating theory, modeling and simulation with computational and experimental science in a transdisciplinary, team science research environment. The Institute’s mission is to solve some of society’s most important problems affecting life sciences, social sciences and human health through transdisciplinary informatics research and education.
As a member of the Nutritional Immunology and Molecular Medicine Laboratory (NIMML) in VBI, the Research Assistant Professor of Translational Systems Biologist will work on the NIAID-funded project: Modeling Immunity to Enteric Pathogens (MIEP). The primary focus of this position will be innovative, collaborative research related to mechanisms of mucosal immune regulation during infection with enteric pathogens, including Enteroaggregative Escherichia Coli (EAEC), Clostridium difficile and Helicobacter pylori. The Translational Systems Biologist will collaborate and coordinate efforts with clinical researchers and computer modeling personnel, and will provide a plan for studies in additional NIAID Category A-C enteric pathogens. The Translational Systems Biologist will also coordinate with the bioinformatics personnel in NIMML and MIEP and assist in the creation and maintenance of immunological databases related to analyses of high-throughput transcriptomics and proteomics data in the context of infectious and immune-mediated diseases.
Responsibilities will include:
•Actively collaborates in projects related to mathematical/computational modeling and bioinformatics analyses of mucosal immunity or any other related projects as instructed by the NIMML Director.
•Represents the NIMML and VBI and the Institute by participating and presenting at conferences, seminars, workshops, etc., as required.
•Ensures compliance with laboratory, departmental, and university policies related to chemical safety, biosafety, IACUC, IRB and IBC.
•Publishes original results of research in peer-reviewed, high-impact scientific journals.
•Trains, mentors and supervises students, post-doctoral associates, and technicians in the laboratory on research initiatives, experimentations and laboratory protocols.
•Submits research proposals to funding agencies and establishes a programmatically integrated research portfolio as PI and Co-PI.
•Takes the initiative in finding solutions to scientific problems that arise in day-to-day research.
•Routinely communicates research progress with supervisor, peers and other lab staff.
•Participates in NIMML management and staff meetings.
The successful candidate will have:
•Ph.D., in immunology, inflammation, cell and molecular biology, bioinformatics, or related field.
•Training in immunology, translational science, systems biology, immunoinformatics or inflammation research.
•Candidate should be able to demonstrate the ability to establish and maintain a vigorous externally funded research program aligned with the NIMML programmatic goals.
•Demonstrated expertise in mRNA and miRNA sequencing analyses.
•Demonstrated expertise in flow cytometry, mass cytometry, and cell culture assays.
•Demonstrated record of publication in high impact journals peer-reviewed journals.
•Demonstrated expertise in animal experimentation in the context of infectious or immune-mediated diseases.
•Excellent organizational, time management, and multitasking skills.
•Capable of working in a team science environment with a strong inclination for transdisciplinary and translational science.
•Creativity, independence, and self-motivation, with good communication skills.
Preferences will be given to candidates who possess domain expertise in mucosal immunology; expertise in software development; grant writing experience; previous expertise in immunoinformatics and systems biology; and computational/bioinformatics skills and expertise.