In Vivo Resource and Product Development Manager

The Jackson Laboratory
Job Location: 
Sacramento, CA
Job Description: 

Develop and execute a product development plan for the PDX resource to ensure JMCRS can meet the mid and long-term surplus needs of the Lab. These products will address the needs of the market in a manner that is consistent with the Laboratory’s mission. The incumbent has overall responsibility for the day to day operations of the PDX Resource development team as well as ensuring the seamless transfer of new products into operations.

Serve as Study Director for product development collaborations with ultimate accountability for ensuring studies are executed according the agreed on study plan, without deviation and on budget.

Responsibilities Include:
Oversee all lab/ technical aspects of the PDX resource development and PDX-Avatar platform development. Manages the development of PDX and biobanking of models. Executes the PDX product development budget, support Business Unit Manager in establishing market development and product launch plan. Provide leadership to staff within the reporting structure ensuring they have adequate training and mentoring to support the in vivo services drive for scientific quality and operational efficiency in support of the labs goals and holding them accountable for the same. Ensure staff understand and are compliant with all policies, procedures and practices established by the organization thus ensuring the most efficient operation of the laboratory to provide clients with the highest quality scientific service while meeting organizational operations and financial targets. This includes AXAPTA data entry, LIMS data entry, PPE requirements and general lab operations. Serve as PDX technical/scientific liaison with internal and external collaborators. Publications are an expected outcome.


Ph.D. in a life science is required.
Minimum of 4 years’ experience in preclinical modeling in cancer; preferably in PDX or cell line based models. Documented in vivo pharmacology capabilities.
Working knowledge of the molecular drivers of cancer pathways and the implications for drug discovery/development.
Knowledge of supervisory processes and techniques of leadership as would normally be acquired through at least 4 years of supervisory or leadership experience.
Documented ability to develop and lead technical teams.
Excellent oral and written communication skills.

Contact Information: 

Interested individuals please submit your resume to job posting #4051 at

About Our Organization: 

The Jackson Laboratory ( is an independent, nonprofit biomedical research institution and a National Cancer Institute-designated Cancer Center with more than 1,500 employees. Headquartered in Bar Harbor, Maine, it has a facility in Sacramento, Calif., and a new genomic medicine institute in Farmington, Conn. The Laboratory’s mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
Founded in 1929, the Laboratory applies its eight decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and empowers the global biomedical community by providing critical data, tools and services. The Laboratory is the world's source for more than 7,000 strains of genetically defined mice, is home of the Mouse Genome Informatics and Mouse Phenome databases, and is a hub for scientific courses, conferences, training and education.
With ever-increasing precision, the Laboratory identifies the genetic and molecular bases of disease and marshals its strengths in genomics and modeling to discover individualized treatments and cures. The Laboratory’s work will make medicine more precise, predictable and personal, improving care, lowering costs and increasing life span and health span.