Layer, Chiang, et al. Genome Biology
Personalis Genome Services provides a vertically integrated solution from NGS sequencing to interpretation with a focus on providing superior, highly accurate results to researchers and clinicians. Our services support researchers engaging in large case-control and family-based genome studies of complex or Mendelian diseases and traits, pharmacogenomics, and cancer. Located in Menlo Park, CA, we are seeking an accomplished, talented Senior Director of Bioinformatics with a track record of success developing novel next generation sequencing tools and algorithms in a commercial or large scale academic setting to join our Team.
Ideal Candidate Profile
You have a strong interest in building cutting edge NGS sequencing and analysis tools/algorithms with a focus on accurate, biologically or clinically actionable results. You love the idea of working together with world experts in a broad variety of domains including sequencing/laboratory platforms, bioinformatics, clinical genetics, pharmacogenomics, and medicine. You thrive in the high energy start-up environment where ideas are rapidly translated into practice and flexibility is critical.
|•||Build and manage a R&D team of bioinformaticians, scientists, engineers and statisticians developing cutting edge tools, databases, and algorithms for improving accuracy of genome sequence alignment, variant calling, and interpretation.|
|•||Actively participate in developing project plans and providing regular updates against milestones.|
|•||Work cross-functionally with other members of the R&D team including laboratory, software engineering, IT, and clinical genetics teams to deliver robust research and clinical solutions.|
|•||Work with the software engineering team to spec, develop, test and deploy informatics software solutions and tools.|
|•||Work with marketing, sales, and ops teams to enable commercial success including interfacing with thought leaders, external collaborators/customers, presenting at conferences, publishing papers regarding novel bioinformatics approaches.|
|•||PhD in bioinformatics, computational biology, genetics, or computer science, or related degree.|
|•||8+ years experience developing new informatics processes, tools for analyzing genetic/genomic data, ideally in a commercial environment.|
|•||Deep expertise in next generation DNA sequencing data, algorithms, and common platforms.|
|•||Experience in analyzing, interpreting, and integrating large-scale biological datasets, including genetics, genomics, pathway, and molecular data.|
|•||Strong algorithms experience for sequencing alignment and variant calling.|
|•||Strong knowledge of clinical genetics, statistical genetics highly desirable.|
|•||Experience in database design, development, maintenance, and optimization.|
|•||Knowledge on a wide variety of genetic, genomic, and biological data in the public repositories.|
|•||Programming skills and hands on experience with linux systems, scripting and programming languages in Python, Perl, R, Java, C++ MySQL and high performance computing environments.|
|•||Solid publication record on analyzing NGS human genome data.|
|•||Demonstrated ability to collaborate with research scientists, software developer, and external collaborators.|
Personalis is an equal opportunity employer. Personalis offers a competitive compensation and benefits package. If interested, please submit a letter of interest, resume and salary requirements to email@example.com.
Personalis is a genome-scale diagnostics company with a mission to pioneer genome guided medicine. Our priority is to obtain the most accurate genetic data from each sample, and then to draw the most reliable medically-focused conclusions from these. Our tests are based on whole human genome and exome sequencing, conducted in our state-of-the art laboratory. We analyze results utilizing proprietary databases, advanced human reference sequences, and sophisticated algorithms.