Postdoctoral Fellow

Organization: 
EMBL-EBI
Job Location: 
Cambridge, United Kingdom
Salary: 
Competitive
Benefits: 

Excellent sporting facilities, a free shuttle bus to campus and other nearby centres and an attractive working environment set in 55 acres of parkland.

Job Description: 

We are looking for an outstanding, highly motivated Postdoctoral fellow to investigate spatio-temporal control in cell-cycle regulation. This exciting interdisciplinary research opportunity will be jointly coordinated by the Beltrao group at the European Bioinformatics Institute (EMBL-EBI) and the Quantitative Cell Biology group, headed by Dr Silvia Santos, at the MRC-Clinical Sciences Centre in Imperial College London.

The Beltrao group is interested in studying the molecular sources of phenotypic novelties. Within the broad scope of this evolutionary problem the group is developing computational tools to study the function, specificity and evolution of post-translational regulatory networks. More details can be found at http://www.ebi.ac.uk/beltrao.

The Quantitative Cell Biology lab aims to monitor how signalling molecules are organised into circuits, how these circuits are spatio-temporally regulated and how they remodel during cell fate decisions. The group's research program combines multi-disciplinary approaches including advanced live-cell imaging, chemical biology, molecular biology and mathematical modelling. See more at http://www.csc.mrc.ac.uk/Research/Groups/EPI/QuantitativeCellBiology.

The successful candidate will study spatio-temporal regulation in cell-cycle control under different biological contexts. Projects include: understanding remodelling of cell cycle regulatory networks during cellular differentiation and cell fate decisions and investigating the evolution of cell-cycle networks. The proposed studies will involve quantitative analysis of single-cells and cell populations by advanced live-cell imaging and reverse engineering approaches for cell-cycle network reconstruction.

Informal enquiries about the post can be directed to either pbeltrao@ebi.ac.uk or silvia.santos@imperial.ac.uk

EMBL-EBI is located on the Wellcome Trust Genome Campus near Cambridge in the UK and is a world-leading bioinformatics centre. We provide a dynamic, international working environment and have close ties with both the University of Cambridge and the Wellcome Trust Sanger Institute. EMBL-EBI staff enjoy many benefits including excellent sports facilities, a free shuttle bus to Cambridge and other nearby centres, an active sports and social club and an attractive working environment set in 55 acres of parkland.

The CSC is a multi-disciplinary, highly collaborative research centre funded by the Medical Research Council (MRC). It offers state of the art core facilities, which include light-microscopy and super-resolution microscopy, proteomics and other services. For more information, please visit www.csc.mrc.ac.uk

Requirements: 

The successful applicant must hold a PhD in areas relevant to Quantitative and Systems Biology and strong expertise in programming and image analysis and/or modelling of dynamical systems is required. Previous experience in cell biology and microscopy would be considered an asset.

The post-holder should enjoy working in a highly collaborative and interdisciplinary environment. Good written and oral communications skills are essential.

Contact Information: 

Please apply online through www.embl.org/jobs