The Stitzel Lab at The Jackson Laboratory for Genomic Medicine in Farmington, CT is seeking a Research Assistant II/ III. The Stitzel Lab investigates how variation in regulatory, non-coding regions of our genome contributes to cellular dysfunction, with a particular emphasis on pancreatic islet function and diabetes.
The main role for this technician will be to perform a variety of biochemical, molecular, and cellular experiments to investigate the genomics and epigenomics of metabolic disease and type 2 diabetes. Techniques include, but are not limited to, chromatin immunoprecipitation, molecular cloning, immunofluorescence, quantitative PCR and allelic nucleic acid analyses. The technician will be responsible for processing human tissue samples and cultured cell lines for these analyses. Experience with ES/iPS cell culture and directed differentiation is preferable. Maintains and coordinates lab activities and departmental policies concerning environmental and infection control, biosafety. May assist with supervision of other technicians and students. Requires the ability to generate and analyze experimental results within reasonable time constraints and compile the data for peer and PI review. Records test results in lab notebooks and computer accurately. Comfortably handles sample collection and cell lines and performs all other duties as assigned.
• Achieves a high level of professional/scientific skill or knowledge in specific area(s) and keeps up with current developments and trends in area(s) of expertise. Knowledge of the scientific principles, methods and processes (technical and/or theoretical) used to conduct a systematic and objective inquiry including experimental design, methods of data collection and analysis, and interpreting and reporting results; ability to operate instruments and equipment; knowledge of related information technology.
• Identifies and develops research objectives, methods and quality control measures based on literature searches; plans methods and techniques to meet research objectives; may modify and/or refine procedures, methods and techniques as needed; identifies and plans for research project resources and methods of data collection. Learns and adopts new procedures.
• Performs tests, procedures and experiments applying specialized skills, knowledge and equipment; modifies and refines techniques and procedures to meet research objectives; manages multiple, concurrent projects or a multi-faceted project. Trouble shoots new protocols.
• Performs statistical analysis; interprets and evaluates results; prepares reports and/or presentations; monitors and collects research data to assess accuracy, validity, and integrity
• Provides oversight of technical programs and administrative activities in a research setting - research laboratories including quality assurance and safety programs; coordinates and manages facilities, equipment, supplies and related resources; monitors environmental risks and quality control; understands and complies with safety standards to maintain a safe environment.
• Clearly and concisely conveys information verbally and in written form; effectively presents ideas to individuals or groups to ensure that they understand the information and message. Presents research results and summaries; adheres to reporting requirements of research project(s); contributes to the writing of publications and reports.
• Instructs and trains staff, students, faculty and/or other clients in the performance of procedures and operation of equipment.
• Responsible for utilization of laboratory equipment, data and expenditures.
• Interacts with all individuals in productive ways to enhance the outcome of the goals of the research program, such as ability to accept and give direction and constructive criticism. Shows respect and maintains professional attitude to all lab members and outside collaborators.