Genetic Resource Science (GRS) at The Jackson Laboratory, located in Bar Harbor, Maine has a key position open for a KOMP2 Program Manager. This position will be responsible for leading a research and resource functional team, developing, optimizing and executing a core operation essential to the GRS program. This includes, but is not limited to, management of process and throughput, data collection and QC, troubleshooting and technology development, reporting and manuscript/grant preparation, and supervision of technical staff. The incumbent is expected to manage the core function independently, interact effectively with multiple PIs in GRS and JAX, and work with external collaborators and users.
As the Program Manager, the successful applicant will develop and manage the JAX KOMP2 embryonic lethal phenotyping platform. The mission of the JAX KOMP2 Program is to generate and phenotype a genome-wide collection of more than 800 mouse strains over the next several years as part of an international effort to functionally annotate the mouse genome and generate mouse models of human disease. We expect that approximately one third of all knockout strains will be lethal prior to birth. This is an exciting opportunity to participate in a high-profile program to build and implement a pipeline from the ground up, with a particular focus on developing high-resolution 3D imaging approaches to capturing and annotating embryonic phenotypes. The incumbent will lead a team of technical staff in the production, collection, imaging and annotation of embryos from lethal strains. She/he will play a key role in refining imaging procedures and analysis tools, and will participate in R&D efforts to develop new embryonic lethal phenotyping modalities. Finally, the Program Manager will work closely with other KOMP2 and international consortium members to ensure data collection and reporting standards, and will be responsible for meeting data collection and upload timelines.