Layer, Chiang, et al. Genome Biology
Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron markets medicines for eye diseases, colorectal cancer, and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including hypercholesterolemia, oncology, rheumatoid arthritis, allergic asthma, and atopic dermatitis.
REGN is expanding its genomics efforts and operations, building upon its strengths in mouse genetics (VelociGene®; VelocImmune® and related technologies) and genetics-driven drug discovery and development (e.g. Interleukin-1 blocker rilonacept, FDA approved in 2008; PCSK9 antibody alirocumab, in Phase 3; and several other important pipeline medicines). Specific activities being scaled up will include whole exome and whole genome sequencing projects, functional biology and mouse genetics for disease modeling, and translational research integrating genetics discovery research with REGN's growing pipeline development efforts.
Along with others in industry and academia, Regeneron has long seen human genetics and genomics as essential platforms for facilitating and enabling drug discovery and development; we believe technological advances and other trends now make it possible to more fully realize this potential. Goals for REGN's programs include target discovery, indication discovery, and patient-disease stratification through the use of human genetics and related genomic sciences.
Regeneron’s interests encompass a breadth of different areas spanning Mendelian and family frameworks, large scale population genetics (both common and rare variants), and gene-gene interactions. The company will rely on its internal assets and technologies as well as continue to collaborate with investigators around the world in pursuing exciting genetics discovery projects. Regeneron is looking for talented and motivated individuals to join the company, complement internal teams and resources, and help lead these exciting programs and expanded efforts.
We are looking for a Research Associate - Sequencing, who will report to the Manager - Sequencing Lab and is responsible for managing NGS library construction, exome capture, and Illumina sequencing.
This Research Associate will:
- Perform Illumina flowcell preparation (cBot) and start sequencing runs on the latest model Illumina or equivalent next generation sequencing instruments.
- Perform routine sequencer maintenance procedures.
- Perform regularly scheduled diagnostic tests on sequencer.
- Work with sequencer vendor to quickly resolve instrument failure instances.
- Enter sequencing parameters into LIMS and maintain accurate sample records.
- Implement SOPs to maintain to maintain stringent performance requirements, including throughput and quality metrics.
This position requires a minimum of a Bachelor’s Degree and at least 1-2 years of experience working in a molecular biology lab.
This experience should include:
- Experience with operating DNA sequencing using Illumina or equivalent DNA sequencing instruments.
- Experience in lab automation with liquid handling robots.
- Experience in molecular biology techniques such as PCR, gel electrophoresis, and restriction enzyme mapping.
- Experience with using LIMS
This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry.
Apply today and learn more about Regeneron’s unwavering commitment to combining good science & good business.
To all recruitment agencies: Regeneron is using the agency management company, Candex - www.candex.com. Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method without a valid written search firm agreement in place for this position will be deemed the sole property of Regeneron. No fee will be paid
in the event the candidate is hired by Regeneron as a result of the referral or through other means.
Regeneron is an equal opportunity employer and is an affirmative action employer.
To apply for this position, please CLICK HERE