Senior Lab Technician, Next Generation Sequencing

New York Genome Center
Job Location: 
New York, NY
Job Description: 

We are looking for a highly motivated, independent but team-oriented Senior Laboratory Technician with strong expertise in Next Generation Sequencing with the Illumina platform.

Job duties will include:
•Maintain, troubleshoot and perform day-to-day work on the Sequencing equipment (e.g. Illumina HiSeq2500, cBots);
•Carry out procedures associated with DNA sequencing on the Illumina sequencing platform; including DNA library preparation, sample quantification & preparation, and Sequencer operation;
•Implement next generation sequencing applications for genomic DNA, targeted capture, ChIP-seq, RNA-seq, small RNA-seq, and bisulfite sequencing;
•Analyze current process procedures and provide feedback for their optimization and improvement, documenting processes, improvements to methods, and troubleshoot assays as needed;
•Perform the quality control of the samples and the raw sequencing data;
•Conduct other laboratory work as needed;
•Contribute to the writing of project proposals and manuscripts describing the methods.


•Bachelors degree in Molecular Biology, Biotechnology, Biochemistry or related field plus laboratory experience in nucleic acid research required;
•2+ years of demonstrated experience with Next Generation Sequencing instruments including Illumina platform;
•Solid knowledge of molecular biology equipment and related protocols (including RNA and DNA preparation, RNA and DNA quantification, hybridization, PCR, multiplex amplification and bead-based solutions);
•Array experience preferred, ideally on the Illumina iScan platform;
•Familiarity with Microsoft Word, Excel, PowerPoint, and LIMS-based systems for project management;
•Previous experience as a technician in a molecular biology laboratory preferred, exposure to bioinformatics is a plus;
•Good general laboratory and organizational skills including the ability to work independently and efficiently are essential;
•Ability to multitask is a must, along with an orientation toward teamwork and cooperation;
•Strong creative thinking and problem solving skills;
•Excellent communication skills required;
•A high tolerance for change will be beneficial as NYGC is in start-up mode and the environment will morph rapidly.

Contact Information: 

Submit your CV or resume to

About Our Organization: 

The New York Genome Center (NYGC) is an independent, non-profit organization that leverages the collaborative resources of leading academic medical centers, research universities, and commercial organizations. Our vision is to transform medical research and clinical care in New York and beyond through the creation of one of the largest genomics facilities in North America, integrating sequencing, bioinformatics, and data management, as well as performing cutting-edge genomics research.

Additional information about New York Genome Center can be found at