Bioinformatician – Staff Scientist

The Genome Institute at Washington University in St. Louis
Job Location: 
Saint Louis, MO
Commensurate with experience
Job Description: 

The Genome Institute at Washington University in Saint Louis is looking for a Bioinformatician to work with a dedicated team of researchers investigating Cancer Genomics. As one of only three NIH funded large-scale sequencing centers in the United States, The Genome Institute is involved in numerous collaborations and projects studying the genomics of myriad tumor types.

Responsibilities include but are not limited to:
* Evaluation and design of analysis plans for sequencing-based projects studying the genetic basis of cancer, tumor clonality, tumor progression, tumor treatment response and other cancer-related studies.
* Cooperation with computer scientists to implement analysis pipelines for analysis of high throughput sequencing data.
* Interpretation and integration of genetic and epigenetic changes in cancer including mutations, gene expression data, epigenetic modification, copy number and structural variation.
* Integrated pathway and gene network analysis related to cancer.
* Interaction with teams of diverse internal and external collaborators including oncologists, computer scientists, biologists, and other geneticists/statisticians.


Required Qualifications:
* Master’s degree with 2 years of experience in research lab operations or equivalent combination of education and experience.

Preferred Qualifications:
* Experience with statistical software packages such as R or SAS.
* Strong communication skills.
* Ability to work effectively in a team.
* Independent and self-motivated.
* Experience analyzing large genomic data sets. Prior experience with sequencing data is a plus, but not required.
* Experience programming in Perl, C/C++ or related languages.

Contact Information: 

Contact us at or apply online at

About Our Organization: 

The Genome Institute has been at the forefront of genome research since its inception in 1993 and has been a part of major scientific projects such as the Human Genome, 1000 Genomes and TCGA (The Cancer Genome Atlas) Projects. The Genome Institute is a world-leader in the generation and analysis of genomic sequence data and uses this data to extend biological knowledge of the human genome and provide clinically relevant sequence analysis aimed at understanding human diseases (such as cancer and Alzheimer's disease). In addition, the Institute fosters public understanding of genomic science through various educational and outreach efforts.