Mechanical Staff Engineer

Pacific Biosciences
Job Location: 
Menlo Park
Job Description: 

Pacific Biosciences is seeking a disciplined mechanical engineer with experience designing complex, high-volume cross-functional instrumentation. The DNA sequencing market that Pacific Biosciences is competing in requires continual development of novel concepts that can be proven and transitioned to a manufacturing environment. The candidate will be responsible for creating and developing these new concepts for our existing and upcoming products. The ideal candidate is knowledgeable in instrument definition, design, testing, and troubleshooting. A strong work ethic and commitment to solid documentation practices are a must. Work is fast paced and multifaceted, touching on many additional engineering disciplines: thermal, chemical/biological, optical, electrical, structural, and software. The perfect candidate will be comfortable shifting priorities quickly and getting hands-on to diagnose and solve technical issues. They must be comfortable working closely with others and giving/receiving constructive design feedback.


The candidate will be responsible for working on and leading cross-functional teams to diagnose issues, gather requirements, define specifications, develop and test concepts, then execute on designs with input from many functional groups. This role will provide support to manufacturing, field service, and internal users and to improve reliability, manufacturability, and serviceability of our current and future products.


B.S. or more advanced degree in mechanical engineering or related field.

10+ years industry experience

Broad instrumentation experience, including optics, thermals, vibration, fluidics, robotics, automation, or packaging, expected

Advanced understanding of volume production of complex instrumentation strongly desired

Experience following strict product development processes required

Experience with molded consumables is a plus

Basic software scripting experience a plus

Proficient in good documentation practices

Strong communication skills, including sharing and accepting ideas with many sources

Capable of operating autonomously and disciplined enough to follow established best practices and guidelines

Proficiency in Solidworks or equivalent 3D modeling experience

Drafting experience using ASME Y14.5-2009

Machine Shop experience preferred

About Our Organization: 

Pacific Biosciences’ mission is to transform the way humankind acquires, processes and interprets data from living systems through the design, development and commercialization of innovative tools for biological research. The company has developed a novel approach to studying the synthesis and regulation of DNA, RNA and protein. Combining recent advances in nanofabrication, biochemistry, molecular biology, surface chemistry and optics, Pacific Biosciences has created a powerful technology platform called single molecule, real-time, or SMRT™, technology. SMRT technology enables real-time analysis of biomolecules with single molecule resolution, which has the potential to transform the understanding of biological systems by providing a window into these systems that has not previously been open for scientific study.