Scientist, Bioanalytical (Temp)

Organization: 
Ardea Biosciences/Astra Zeneca
Job Location: 
San Diego, CA
Salary: 
Commensurate with position
Benefits: 

N/A

Job Description: 

Ardea currently has an opening for a Scientist in our Bioanalytical section of our Translational Sciences Department. This position will perform bioanalytical LC/MS/MS method development, validation and sample analysis to quantify drugs and metabolites in biological matrices under GCP and GLP guidelines.
*This is a temporary position. The length of assignment is anticipated to be for 6 months.
Responsibilities include:
• Primarily responsible for developing and validating robust and reproducible LC/MS/MS methods for the quantitation of complex analytes in biological matrices under GLP and FDA/EMA guidelines.
• Extract and analyze biological samples under GCP and GLP guidelines.
• Analyze technical data to determine trends and draw conclusions
• May serve as study director/principal investigator with overall responsibility for bioanalytical conduct.
• Maintain, operate, and troubleshoot API4000 and API5000 LC/MS/MS instruments and other analytical equipment.
• Maintain research records and lab notebooks in a concise, legible and GLP compliant manner.
• Write and revise departmental SOPs, validation and analytical reports.
• Ensure adherence to protocols, SOPs, GCP and GLP guidelines.
• Assist in the preparation of any regulatory submissions.
• May provide training to less experienced departmental staff.
• Evaluate and recommend new techniques in sample purification, analysis, and automation.

Requirements: 

Requirements
• B.S., M.S, or PhD in Analytical Chemistry or other related disciplines.
• At least five years of CRO or industrial hands-on experience in bioanalytical method development/validation of complex analytes using LC/MS/MS techniques.
• In-depth knowledge of LC/MS/MS techniques and sample preparation are a must.
• In-depth knowledge of GLP guidelines.
• Prior experience serving as a study director/principal investigator is a plus. This experience includes development of study protocols, SOPs, validation and analytical reports; preparation and/or review of study binders ensuring compliance.
• Experience with Watson LIMS and Analyst a plus, but not required.
• Strong communication skills, as well as the ability to be a team player.

Contact Information: 

Apply today at: www.ardeabio.com/careers

About Our Organization: 

Ardea Biosciences, a wholly owned subsidiary of AstraZeneca, is headquartered in San Diego, CA. We are a biotechnology company focused on the development of small-molecule therapeutics for the treatment of serious diseases.