Sponsor: Rubicon Genomics
Recording Date: 2/19/2014
Recording Time: 1 hour
EMBL-EBI staff enjoy many benefits including excellent sporting facilities, a free shuttle bus to Cambridge and other nearby centres, an active sports and social club and an attractive working environment set in 55 acres of parkland.
We are looking for a motivated Research Scientist to join the Beltrao Group at the European Bioinformatics Institute (EMBL-EBI) which is located on the Wellcome Trust Genome Campus near Cambridge in the UK.
The Beltrao group is interested in understanding the molecular sources of phenotype novelties, or in other words, how genetic variability introduced at the level of the DNA is propagated through protein structures and interaction networks to give rise to phenotypic variability. Within the broad scope of this evolutionary problem, the group is studying the function and evolution of post-translational regulatory networks. In collaboration with mass spectrometry labs, a growing resource of post-translational modifications (PTMs) from different species (PTMfunc.com) is being developed to study the functional relevance and evolutionary properties of post-translational networks. More details can be found at http://www.evocellnet.com
The successful candidate will contribute to the on-going efforts to;
• study and predict enzyme specificity and PTM networks;
• model data on conditional changes of PTM abundance to study signalling specificity and functional co-regulation of PTMs; and
• to develop methods to prioritise functionally relevant PTMs within large-scale datasets.
The ideal applicant should hold a degree in either mathematics/engineering or biological sciences and have a Ph.D in computational biology. A background in biology is recommended and a good understanding and previous usage of methods in some of the following fields is considered an advantage: biological network analysis, structural bioinformatics, linear motifs, evolution of interaction networks, comparative genomics, and data mining. Candidates should have programming experience and ideally be familiar with Python or Perl.
The post holder should feel comfortable interacting with others in an interdisciplinary setting, since research will be run in close collaboration with experimental groups, and should have good written and oral communication skills. Excellent interpersonal skills are also required.
Please apply online through www.embl.org/jobs
EMBL-EBI is a world-leading bioinformatics centre. We provide a dynamic, international working environment and have close ties with both the University of Cambridge and the Wellcome Trust Sanger Institute.