QC and Primary Analysis - Project Leader

The Genome Analysis Centre (TGAC)
Job Location: 
Norwich, UK
£33,750 - £45,000
Job Description: 

To work with the Sequencing Informatics group leader to develop TGAC’s strategy for data primary analysis and quality assessment. - To establish best practice guidelines and SOP for data management and handling, and reporting strategies. - To influence and recommend the sequencing strategy of the Centre driven by technological advances and by programme needs. - To support, mentor and manage a team of scientific programmers. - To ensure that the bioinformartics primary analysis pipelines are state of the art and at the leading edge of technological advances and delivers data to meet the TGAC sequencing programme objectives. This will be key to provide an efficient and cost-effective National Capability for UK bioscience/ - To initiate or act as Co-PI on sequencing analysis, tools, resources or similar grant submissions. - To communicate the work of TGAC in oral and written presentations and to publish novel technological developments in scientific journals; - To network widely with academic and industrial groups on the Norwich Research Park, throughout the UK and internationally, including with the Wellcome Trust Sanger Institute, the European Bioinformatics Institute, other genomics facilities nationally and internationally and with biological scientists applying genomics technologies to novel research questions.


PhD in a relevant discipline, e.g. computer science, bioinformatics.

Knowledge of methods of analysis of biological sequence data especially next-generation sequence data.

Experience in bioinformatics related to high throughput DNA sequencing.

Excellent communications skills.

Contact Information: 

For more information and to apply please visit http://jobs.tgac.ac.uk/Details.asp?vacancyID=3790

About Our Organization: 

The Genome Analysis Centre (TGAC) is a vibrant, contemporary research institute and registered charity, working in an area of rapid technological development and innovation.

TGAC is strategically funded by the BBSRC to lead the development of a skill base in bioinformatics and a genomics technology platform for UK bioscience. The Institute is located on the Norwich Research Park, together with its partners: the John Innes Centre, the Institute of Food Research, The Sainsbury Laboratory, the University of East Anglia and the Norfolk and Norwich University Hospital. The research park has an excellent reputation for research in plant and microbial sciences, interdisciplinary environmental science and food, diet and health, to which TGAC contributes strengths in genomics and bioinformatics. Close links exist between the NRP partners and new opportunities for collaboration in exciting new initiatives are under development. The NRP recently received £26M of government investment to facilitate innovation and further develop infrastructure to attract science and technology companies to the Park to enhance the vibrant environment and realise economic impact from research investment.

TGAC is a UK hub for innovative Bioinformatics through research, analysis and interpretation of multiple, complex data sets. It hosts one of the largest computing hardware facilities dedicated to life science research in Europe. This has been boosted recently by an e-Infrastructure grant to expand the data storage capacity to a multi-petabyte unit, deploying a high performance cluster and large-memory server enabling the allocation of processes requiring several terabytes of computing memory.

TGAC’s state of the art DNA sequencing facility operates multiple complementary technologies for data generation that provide the foundation for analyses furthering our fundamental understanding of genomes and how they function. We aim to be at the forefront of technological advances and are developing and implementing technologies to generate and analyse new types of data. We also develop novel platforms to provide access to computational tools and processing capacity for multiple academic and industrial users and promoting applications of computational bioscience. TGAC has one fully owned subsidiary, Genome Enterprise Ltd (GEL) via which it offers genomic and bioinformatics services on a trading basis and works with commercial providers on a partnership basis. TGAC also receives specific funding to enable knowledge exchange programmes which are supported across the institute teams.