Principal Scientist - NGS/GWAS Bioinformatician/Computational Biologist - Predictive Toxicology
(position located in Cambridge, MA)
The Department of Comparative Biology and Safety Sciences is seeking a highly motivated and experienced Bioinformatician/Computational Biologist to support predictive toxicity screening and hazard identification in preclinical drug development.
The position will be based at Amgen’s Cambridge, Massachusetts site with the primary responsibility of collaborating with toxicologists/biologists by leveraging information on biological pathways relevant to toxicity and using novel, cutting edge, computational algorithms to study internal and external high-content data types such as gene expression data, GWAS, next-generation sequencing.
The candidate is expected to proactively interact with the Bioinformatics community in the Boston area and foster strong relationships that would advance our computational capabilities with the ultimate goal of promoting better solutions to understand mechanisms of toxicity as well as potential toxicity screens. By networking and collaboratively working with external experts and Amgen scientists across multiple sites, the successful candidate will integrate acquired knowledge into our efforts to inform decision-making in preclinical drug development.
Developing state-of-art computational algorithms and utilizing complex high-content data for toxicity prediction applications are anticipated to be a substantial component of this job and the candidate is expected to provide leadership and expertise in these domains with minimal supervision.