Fred Hutchinson Cancer Research Center, home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation, the Center’s five scientific divisions collaborate to form a unique environment for conducting basic and applied science. The Hutchinson Center, in collaboration with its clinical and research partners, the University of Washington and Seattle Children’s, is the only National Cancer Institute-designated comprehensive cancer center in the Pacific Northwest. Join us and make a difference!
About the Department:
A new laboratory at the Fred Hutchinson Cancer Research Center, Division of Human Biology, is looking for a highly motivated, recent Ph.D. graduate or an M.D. The candidate would join the laboratory of David MacPherson where he/she will use genomic approaches to interrogate new genes implicated in small cell lung carcinoma (SCLC). SCLC is a highly metastatic neuroendocrine lung tumor for which there are currently no effective therapies over the long term. Our lab has developed new mouse models for SCLC and also has a large collection of human patient samples from which we have identified new SCLC-mutated genes. The candidate will use mouse lung cancer models along with cell culture systems and human samples to study the function of SCLC-mutated genes. Our aim is to elucidate the pathways through which SCLC driver genes act and to harness such knowledge in the design of new therapeutic approaches. We welcome candidates with interests in applying novel therapeutics and advanced tumor imaging to mouse lung cancer models. We also study the pediatric cancer retinoblastoma and have opportunities for study of retinoblastoma mutated genes in development and cancer.