Senior Scientist

Organization: 
Caliper, a PerkinElmer Company
Job Location: 
Alameda, CA
Job Description: 

Caliper, a PerkinElmer company is a leading provider of cutting-edge technologies enabling researchers in the life sciences to create life-saving and enhancing medicines and diagnostic tests more quickly and efficiently. Caliper’s Life Sciences & Technology (LST) business unit has compiled numerous best-in-class solutions and is aggressively innovating new technologies to bridge the gaps that exist in bringing in vitro assays to in vivo results and ultimately into cures for human disease. With a keen focus on clinically-relevant experimentation, Caliper’s portfolio of offerings includes state-of-the-art microfluidics, lab automation & liquid handling, optical imaging technologies, and discovery & development outsourcing solutions.

Our company represents a community of intelligent, highly-motivated people dedicated to working together as a team to improve the human condition through innovation in life sciences research. Caliper’s customers and partners include leading pharmaceutical companies like Pfizer, GlaxoSmithKline, Sanofi-Aventis, Novartis, and AstraZeneca, among others.

If you are committed to making a significant difference worldwide, we invite you to learn more about the amazing opportunities that await you at PerkinElmer.

Senior Scientist (#4233): Alameda, CA

We are recruiting for the following regular full-time job opportunity as a Senior Scientist. If you would like to learn more about this position, please see our PerkinElmer Careers Page, search for North America, then Senior Scientist (Job Code 4233). All applicants must apply online for consideration.

Our LST group is seeking a Senior Scientist to support sustaining activities for systems development of new imaging platforms and instrument sales for our in vivo entity under LST at the Alameda site while providing a bridge between the transitions of probes from preclinical to clinical use by performing critical experiments to define future instrument specifications.

Responsibilities:
• Animal modeling studies with bioluminescent, fluorescent and CT readouts in a longitudinal format.
• Design of experiments that are hypothesis and biomarker pathway driven for preclinical and PK/PD studies.
• Conception and implementation of customer driven study designs that use different imaging modalities in oncology, infectious, CNS and cardiovascular disease states.
• Cross functional interactions with engineering, physics and software teams to support hardware and software development.

Requirements: 

• PhD in cell molecular biology, pharmacology, or biochemistry with 2-5y post-graduation
• Proficient in optical imaging techniques, familiarity with other imaging modalities such as ultrasonic imaging, PET/CT and MRI.
• Comprehensive skills in cellular, molecular biology and pharmacology pertaining to small animal experimental techniques, vector construction, gene transfer and expression, DNA/RNA and protein analysis, cell and tissue culture, transfection, in vitro and in vivo drug toxicity and effect, handling in small animals with different tumor types, infectious agents and optical probes.
• Experience with tissue analysis, immunohistochemical and fluorescent insitu hybridaztion techniques is a plus.

QUALIFICATIONS
To perform this job successfully, an individual must be able to perform each of the above listed essential duties satisfactorily. The requirements listed below are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

EDUCATION and/or EXPERIENCE
PhD in cell molecular biology, pharmacology, or biochemistry with 2-5y post-graduation

REASONING ABILITY
Ability to apply principles of logical or scientific thinking to a wide range of intellectual and practical problems. Ability to deal with nonverbal symbolism [formulas, scientific equations, graphs, etc. in its most difficult phases. Ability to deal with a variety of abstract and concrete variables.

PHYSICAL DEMANDS
The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

While performing the duties of this job, the employee is regularly required to sit; use hands to finger, handle, or feel; reach with hands and arms; and talk or hear. The employee is occasionally required to stand and walk. The employee must occasionally lift and/or move up to 10 pounds. Specific vision abilities required by this job include close vision, and color vision.

Contact Information: 

For consideration or to learn more information about this position and other career opportunities, go to http://www.perkinelmer.com/ourcompany/careers/careeropportunities/defaul...

About Our Organization: 

As a global technology leader, PerkinElmer is taking action to harness the power of insights and transform them into knowledge to deliver innovative, differentiated solutions for our customers. From critical therapeutic and disease research and prenatal screening, to environmental testing and industrial monitoring, we are actively engaged in improving health and advancing quality and longevity of life all around the world.

From multi-vendor laboratory services, software and informatics, to clinical lab testing and unparalleled customer care; we have the people, tools and resources to help customers solve their business and scientific goals. Our core competencies, coupled with our commitment to excellence, provide a strong foundation for delivering optimal service and support. By encouraging exploration, ingenuity and integrity, together with teamwork and employee development, at PerkinElmer we live our mission, every day.

If you have an interest in becoming a part of a fast growing, innovative company and possess the skills to excel in the position posted, please submit your resume at http://www.perkinelmer.com/ourcompany/careers/careeropportunities/defaul.... To learn more about this or other career opportunities and/or to learn more about the possibilities with PerkinElmer go to: www.perkinelmer.com. If you have an interest in becoming a part of a fast growing innovative company and possess the skills to excel in the position apply today!