Senior Scientist

Organization: 
Caliper, a PerkinElmer company
Job Location: 
Alameda, CA
Job Description: 

This role will support sustaining activities for reagent development and instrument sales for in vivo entity for our Alameda site while providing a bridge between the transitions of probes from preclinical to clinical use by performing critical experiments to define future instrument specifications.

Responsibilities:
· Animal modeling studies with bioluminescent, fluorescent and CT readouts in a longitudinal format.
· Design of experiments that are hypothesis and biomarker pathway driven for preclinical and PK/PD studies.
· Conception and implementation of customer driven study designs that use different imaging modalities in oncology, infectious, CNS and cardiovascular disease states.
· Cross functional interactions with engineering, physics and software teams to support hardware and software development.

Requirements: 

· PhD in cell molecular biology, pharmacology, biochemistry with 2-5y post-graduation
· Proficient in optical imaging techniques, familiarity with other imaging modalities such as ultrasonic imaging, PET/CT and MRI.
· Comprehensive skills in cellular, molecular biology and pharmacology pertaining to small animal experimental techniques, vector construction, gene transfer and expression, DNA/RNA and protein analysis, cell and tissue culture, transfection, in vitro and in vivo drug toxicity and effect, handling in small animals with different tumor types, infectious agents

QUALIFICATIONS

To perform this job successfully, an individual must be able to perform each essential of the above listed essential duties satisfactorily. The requirements listed below are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

EDUCATION and/or EXPERIENCE

PhD in cell molecular biology, pharmacology, biochemistry with 2-5y post-graduation

REASONING ABILITY

Ability to apply principles of logical or scientific thinking to a wide range of intellectual and practical problems. Ability to deal with nonverbal symbolism [formulas, scientific equations, graphs, etc in its most difficult phases. Ability to deal with a variety of abstract and concrete variables.

PHYSICAL DEMANDS

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

While performing the duties of this job, the employee is regularly required to sit; use hands to finger, handle, or feel; reach with hands and arms; and talk or hear. The employee is occasionally required to stand and walk. The employee must occasionally lift and/or move up to 10 pounds. Specific vision abilities required by this job include close vision, and color vision.

Contact Information: 
About Our Organization: 

Caliper, a PerkinElmer company is a premier provider of cutting-edge technologies enabling researchers in the life sciences industry to create life-saving and enhancing medicines and diagnostic tests more quickly and efficiently. Caliper is aggressively developing new technologies to bridge the gap between in vitro assays and in vivo results and then translating those results into cures for human disease. Caliper's portfolio of offerings includes state-of-the-art microfluidics, lab automation & liquid handling, optical and tissue imaging technologies, and discovery & development outsourcing solutions.