Lab Head, DNA/RNA Diagnostics(Phd)

Organization: 
Novartis Institutes for BioMedical Research
Job Location: 
Cambridge, MA
Job Description: 

We are looking for a highly qualified and motivated Ph.D level scientist for the newly established Next Generation Diagnostics (NGDx) group within NIBR. At NIBR, we are dedicated to the development of therapies that improve clinical outcomes for patients. Our goal is to develop a robust and comprehensive molecular profile for each patient, and to deliver the right medicines to the right patients.

The successful candidate is expected to have in depth knowledge in gene expression and gene structure analysis, and extensive experience with Next Generation Sequencing technologies. His/ her responsibilities include:

Lead a group of scientific associates to design and conduct experiments, to interpret and challenge experimental results;
Test and apply new scientific methodologies and techniques to identify and develop innovative solutions to answer experimental / scientific questions
Network internally and externally with other scientists and managers on project activities and therefore develops and maintains internal / external relationships;
Write internal reports and external publications;
Conduct and supervise his/her lab to ensure the compliance with Novartis HSE guidelines and policies.

Requirements: 

Ph.D in Molecular Biology, Biochemistry, Genetics or equivalent plus 3-5 years of working experience in industry or equivalent academia experience. In depth expertise in using bioinformatics tools for the analysis of large NGS data sets is required. “Hands-on” experience with the operation of NGS and associated instrumentation is desired. The ideal candidate will be experienced in using various types of NGS data (Exome, RNA-Seq, etc) for studying the cancer genome and associated signaling pathways. Candidates are required to have good organizational and interpersonal skills. Critical thinking skills and ability to work both independently and collaboratively in a team environment are essential.

Contact Information: 

For more information and to apply, please visit:

http://novartis.avature.net/ngdx/jobDetail?id=163

About Our Organization: 

About Novartis Institute for Biomedical Research:
The Novartis Institutes for BioMedical Research is the global pharmaceutical research organization for Novartis. The NIBR research network is comprised of more than 6,000 scientists, physicians, and business professionals working together across 10 locations around the world to discover innovative medicines that treat diseases with high unmet medical need. Novartis employs more than 2,000 associates in Cambridge, making it the city’s largest private employer and ideally situated in one of the leading life science communities in the world.

NIBR conducts research globally with sites in Emeryville, California; Cambridge, MA; East Hanover, NJ; Basel, Switzerland; Horsham, UK; and Shanghai, China.

About the Next Generation Sequencing Group
The ability to sequence each patient’s genome in great detail, quickly and inexpensively, is changing the practice of medicine. At NIBR, we are dedicated to the development of therapies that improve clinical outcomes for patients. Next generation sequencing and other cutting-edge molecular characterization technologies will be important tools for discovering breakthrough therapeutics, and for delivering the right medicines to the right patients.

NIBR is launching a new Next Generation Diagnostics (NGDx) group at our global headquarters in Cambridge, MA. The NGDx team will leverage cutting-edge technologies such as next generation sequencing for characterizing human tissues, by individual lesions and by pathway signatures relevant to therapeutic response. The goal is to develop a robust and comprehensive molecular profile for each patient. To this end, the group will begin by developing capabilities to characterize therapeutically relevant genetic lesions and pathway signatures in human cancer.

Opportunities exist for genomics scientists, computational biologists, bioinformatics scientists, software and systems engineers, assay development scientists, histopathologists, sample technicians, and biochemists.