Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
Bioinformatics Scientist
Standard package plus stock options
Bioinformatics scientist position targeting clinical analysis of next-generation sequencing testing for neurology, cardiology and oncology. Support of new assay informatics and reporting. Works closely with lab team to develop bioinformatics infrastructure and department of bioinformatics set-up.
PhD preferred. Key experience with 2nd-gen sequencing data intrepretation. Clinical lab experience a plus.
Laverne Drake
Manager Human Resources
Transgenomic, Inc.
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Transgenomic, Inc. is a global biotechnology company focusing on molecular diagnostics products and services. The company has robust businesses in DNA tools products and reagents, a CLIA-certified reference laboratory and a clinical trials support lab division. The company is solidly funded having just completed a $22 million financing and enjoys growing revenues above $30 million a year.