PTB Proteins Induce RNA Looping
Lamichhane, Daubner et al., PNAS
Researchers in the US and Switzerland report that polypyrimidine tract-binding proteins induce RNA looping ― a finding they deduced using FRET, NMR spectroscopy, and in vivo splicing data. They show that two PTB RNA recognition motifs can bind two distant pyrimidine tracts, bringing their 5' and 3' ends in close proximity, thus inducing loop formation.
Bruker, Agilent Reach Deal on Varian Product Lines Purchase
The sale of the product lines to Bruker will clear the way for Agilent to complete its $1.5 billion acquisition of Varian, which is now expected by the end of April.
March 10, 2010
The startup will study the reactions of 1,000 patients' genomes to certain chemotherapeutics.
March 10, 2010
Agilent Lands Aussie Distributor
Pacific Laboratory Products will distribute and support Agilent's line of chromatography columns and supplies in Australia.
March 10, 2010
Biocrates, Chenomx in Metabolic Profiling Technologies Alliance
The firms will combine their mass spec and NMR technologies for metabolomic applications.
March 10, 2010
Institute for Systems Biology Gets $6M Donation
An anonymous California venture capitalist and philanthropist has agreed to donate $6 million over five years to the Institute for Systems Biology.
March 09, 2010
NCI Seeks Molecular Signature Partnerships
The strategic partnerships will use multi-disciplinary research to study how multi-analyte signatures of tumors may be applied to cancer treatments.
March 09, 2010
ZenBio Licenses Metabolic Cell Line from Harvard
ZenBio will offer the cell lines in cryopreserved and cultured forms, as well as contract services including assay development and compound screening.
March 09, 2010
Pressure Biosciences, Target Discovery Partner on Tissue Prep
The companies are collaborating to develop, manufacture, and co-market reagents for use with membrane proteins for diagnostics, therapeutics, and vaccines.
March 09, 2010
Caliper's Q4 Revenues Increase 3 Percent
Caliper easily beat analysts' consensus estimate, which was expected after the firm pre-announced Q4 revenues in January. Its IVIS imaging products were the key driver of revenue growth for the quarter.
March 09, 2010
Biosearch Expands License to Roche IVD Patents
The license will expand Biosearch's participation in the diagnostics field from a provider of oligo components to a provider of kits.
March 09, 2010
NCI, ESTools License Integromics Software
The US cancer institute and the European stem cell consortium have inked site-wide licenses for the gene expression analysis software.
March 09, 2010
NINR to Fund Epigenetics of Chronic Illness Studies
Funded with $1.25 million in 2010, the grants will support studies of epigenetic factors that affect disease symptoms and complications.
March 09, 2010
NIH Plans $24M for Lung Cancer-COPD Genotype, Phenotype Studies
NCI and NHLBI plan to give $12 million each for research into molecular, genetic, and other connections between the two diseases.
March 08, 2010
