Home » Genome Technology

Cover Story

Big Science vs. the R01

Nobody doubts that "big science" can harness the power of the research community to build essential resources and achieve otherwise unthinkable goals. But these programs come at a cost to investigator-driven science — and how will we know when that price is too high?

Big Science vs. the R01

Feature Story

  • Bracing for the Flood

    Like a nesting doll of genome projects, the Data Analysis and Coordination Center for the NIH's Human Microbiome Project is a collaboration within a collaboration.

  • Beyond Darwin's Wildest Dreams

    Evolutionary biology in the genomics era means that researchers have the ability to track the evolution of species right down to the base pair. But with more data come more challenges and questions to answer.

  • Shining the Light

    Targeted enrichment allows for better allocation of resources and still gives scientifically interesting results. But now it is being challenged by lower sequencing costs.

Primer

Markers

Zeitgeist

  • Papers to Catch Up On

    Articles appearing recently in peer-reviewed journals focused on Bayesian phylogenetics, bornavirus, and transmissible cancer in Tasmanian devils.

Careers

  • Follow Your Heart

    Academia isn't for everyone. GT speaks with a career development expert about what to do when you realize the traditional scientist path isn't for you.

My Take

  • An Open Secret

    Ghostwriting practices in biomedicine have come to the forefront — and government, trade organizations, and journals are trying to combat the practice.

Brute Force

  • No Flash in the Pan

    Used for years in everyday electronic devices, flash memory is now making its way into HPC. But is this storage technology really ready for prime time in scientific computing?

Where Are They Now?

In the Clinic

  • Variants for Coronary Disease

    Researchers in a consortium aimed at discovering the genetic basis of coronary disease risk find two variants associated with the disease.

  • MicroRNAs for Risk Prediction

    Genetic variation in the microRNA pathway may influence cancer risk, according to MD Anderson researchers studying patients who relapse.

Calendar & Deadlines

Blunt End