Sequencing and Analysis of the Hydra Genome
Chapman, Kirkness et al., Nature
An international research collaboration reports their sequencing and analysis of the Hydra magnipapillata genome, and compare it to the genomes of several other organisms. "The Hydra genome has been shaped by bursts of transposable element expansion, horizontal gene transfer, trans-splicing, and simplification of gene structure and gene content that parallel simplification of the Hydra life cycle," the authors write. They team suggests that comparisons of the Hydra genome to the reported sequences of other animals have helped them to elucidate the evolution of several of the organism's characteristics.
Entest Turns to Bioinformatics to Discover Therapeutics, Biomarkers for Lung Disease
The firm's bioinformatics-based approach will integrate existing and new data, including -omics information about chronic obstructive pulmonary disease.
W3C Group Plans Ontology for Translational Medicine to Help Bridge Drug Discovery Phases
The World Wide Web Consortium's Health Care and Life Sciences Interest Group is plotting a semantic course to help find ways for pharma to communicate across drug discovery and development phases.
BioDiscovery Turns to the Cloud to Support Collaborative Copy Number Variation Database
The resource, which is integrated with the firm's copy number variation software, is built on the Amazon Elastic Compute Cloud and is intended to help small and medium-sized labs with limited infrastructure budgets.
Eureka Genomics has a two-pronged business model that involves sequencing services and internal discovery projects to identify novel disease-associated microorganisms. Underlying this hybrid model is a portfolio of proprietary bioinformatics tools that the company licensed in 2006 from the University of Houston.
Wash U to Use $14M ARRA Grant to Double Size, Capacity of Genomics Data Center
Wash U's current genomic data center, a 16,000-square-foot facility that houses approximately 5,000 processors and more than 5 petabytes of disk storage, is nearly 90 percent full.
Genedata Analyst, Tibco Spotfire 3.1, GenomeQuest API. Ensembl 57, Mutation Surveyor, Genedata Analyst
Slowly Maturing, Semantic Web Technologies Reach Pilot Project Stage in Pharma
Semantic web proponents at several pharma firms presented pilot project results at this year's Conference on Semantics in Healthcare and Life Sciences in Cambridge, Mass.
Pfizer Partners with IO, Franz on Semantic Proof of Concept to Build Bridges Between Data Resources
The project, intended to serve as a "real-world example" of semantic technology in the pharma setting, was expected to take four to six months to accomplish, but was actually delivered in six weeks.
IBM Donates Supercomputer to Rice University for Collaborative Research with Texas Medical Center
Rice University received a $7.6 million IBM Shared University Research award in the form of a supercomputer, which is ready for projects from researchers across the institutions that are part of Texas Medical Center.
Symyx Technologies Completes HPR Divestiture to Become Pure-Play Scientific Software Shop
The move will permit the firm to focus on the "fast-growing electronic lab notebook market," company officials said.
Danish University Spin-Out Intomics to Help LEO Pharma with Data Analysis
Intomics was co-founded by Danish Technical University researcher Søren Brunak.
