PTB Proteins Induce RNA Looping
Lamichhane, Daubner et al., PNAS
Researchers in the US and Switzerland report that polypyrimidine tract-binding proteins induce RNA looping ― a finding they deduced using FRET, NMR spectroscopy, and in vivo splicing data. They show that two PTB RNA recognition motifs can bind two distant pyrimidine tracts, bringing their 5' and 3' ends in close proximity, thus inducing loop formation.
Biochips in Bangkok: Thailand's Sole Array Lab Plows Ahead with Ag-Bio Projects
Thailand's BIOTEC microarray lab has made progress since its inception two years ago, focusing on projects related to pathogen testing and agricultural research, but running an array lab in a developing country has its share of obstacles.
March 09, 2010
ExonHit, BioMerieux Kill Colon Cancer Program, Continue to Develop Prostate Cancer Dxs
The companies said that "final results from the colon cancer program did not reach the level of performance we were aiming to achieve." The firms, both based in France, are co-developing microarray-based tests that screen for a variety of cancer biomarkers in blood.
March 09, 2010
Refocusing on Product Sales, Gentel Bio Debuts Proteomic Platform
The instrument allows users to run arrays, Western blots, and tissue sections, and is indicative of the direction in which the firm is heading, according to a company official.
March 09, 2010
Cytogenetics Labs ID New Genetic Disorder by Array CGH
Researchers at Signature Genomic Laboratories and three other labs independently identified a total of seven individuals with nearly identical-sized deletions on one of their two copies of chromosome 17.
March 09, 2010
Jami Dover Nachtsheim, Nelson Chan, John Young, Adrian Dillon, Didier Hirsch, Robert Boorstein, David U'Prichard
March 05, 2010
OGT Certified to Offer High-Throughput Agilent Array Services, Embarks on 10K Sample CNV Study
Hungry for high-volume service deals, Oxford Gene Technology has recently made "major" investments in automation, quality control, and personnel in order to offer high-throughput services to its customers.
March 02, 2010
Kreatech Inks Pact with Hungarian University to Develop FFPE Sample-Handling Methods for Array-CGH
Amsterdam-based Kreatech will also seek to take advantage of Semmelweis University's large tissue repository to define putative biomarkers for certain tumor types, including lung cancer, soft tissue, breast, and neuropathological malignancies.
March 02, 2010
Millennium Science to Distribute Golden Helix Software in Australia, NZ
Millennium will provide sales and support for the Golden Helix SNP and Variation Suite, which is aimed at researchers involved in genome-wide association, copy number analysis, and next-generation sequencing research.
March 02, 2010
Anagnostics Taps Peak-Service to Offer Field Support in Europe, US
The deal will help Anagnostics support its first customers for its Hyborg microarray platform, debuted last month, which it plans to ramp up for full commercial launch by the end of the year, according to the company's CEO.
March 02, 2010
