Regulation and Function of miR-218 in Gastric Cancer Metastasis
Tie, Pan et al., PLoS Genetics
Researchers describe a negative feedback system between Robo1, a Slit receptor, and miR-218, wherein “decreased miR-218 levels eliminate Robo1 repression, which activates the Slit-Robo1 pathway through the interaction between Robo1 and Slit2, thus triggering tumor metastasis.” The authors suggest that the restoration of miR-218 supresses Robo1 espression and inhibits tumor cell invasion.
Kalorama Predicts SNP Array Market Will Return to Double-Digit Growth in 2011
Market research firm Kalorama Information recently published an analysis on the market for SNP genotyping tools that largely agrees with vendor forecasts of a second round of genome-wide association studies that will stimulate array sales over the next few years.
March 16, 2010
CombiMatrix 'Not Satisfied' with Pace of Molecular Dx Business Growth
CombiMatrix has found it more difficult than expected to secure reimbursement for its tests, and said that test acceptance has been further constrained by its limited sales and marketing infrastructure.
March 16, 2010
Q&A: Genome Institute of Singapore's Edison Liu on the Future of HUGO, GWAS, and GIS
Re-elected last month as president of the Human Genome Organization, GIS Executive Director Edison Liu sees HUGO as a vehicle to cement the role of developing Asian countries in genomics. He also sees it as a means to broker deals between West and East that foster the application of genomics in medicine and spur economic growth.
March 16, 2010
Rounding Out NimbleGen Workflow, Roche Acquires BioMicro Hyb Station, Mixers
The acquired assets include instruments that are part of the Roche NimbleGen microarray workflow, such as the 4- and-12-bay NimbleGen Hybridization Systems.
March 16, 2010
Biochips in Bangkok: Thailand's Sole Array Lab Plows Ahead with Ag-Bio Projects
Thailand's BIOTEC microarray lab has made progress since its inception two years ago, focusing on projects related to pathogen testing and agricultural research, but running an array lab in a developing country has its share of obstacles.
March 09, 2010
ExonHit, BioMerieux Kill Colon Cancer Program, Continue to Develop Prostate Cancer Dxs
The companies said that "final results from the colon cancer program did not reach the level of performance we were aiming to achieve." The firms, both based in France, are co-developing microarray-based tests that screen for a variety of cancer biomarkers in blood.
March 09, 2010
Refocusing on Product Sales, Gentel Bio Debuts Proteomic Platform
The instrument allows users to run arrays, Western blots, and tissue sections, and is indicative of the direction in which the firm is heading, according to a company official.
March 09, 2010
Cytogenetics Labs ID New Genetic Disorder by Array CGH
Researchers at Signature Genomic Laboratories and three other labs independently identified a total of seven individuals with nearly identical-sized deletions on one of their two copies of chromosome 17.
March 09, 2010
