Genome-Wide Meta-Analysis for Serum Calcium Identifies Significantly Associated SNPs near the Calcium-Sensing Receptor (CASR) Gene
Kapur et al., PLoS Genetics
An international team of researchers reports its genome-wide association study of serum calcium's association with SNPs in or near the calcium-sensing receptor gene on 3q13. "This genome-wide meta-analysis shows that common CASR variants modulate serum calcium levels in the adult general population," the researchers write, adding that their "results show that CASR is a key player in genetic regulation of serum calcium in the adult general population."
Lawrence Corey Named New President and Director of FHCRC
As the successor to Lee Hartwell at the Fred Hutchinson Cancer Research Center, Lawrence Corey said that he would work to expand both basic and clinical research; enhance survival and prevention of cancer and other diseases; improve healthcare to individuals and the entire population; and strengthen existing faculty mentoring programs.
Team Uncovers Ancient Non-Retroviral Virus Sequences in Vertebrate Genomes
American researchers have detected Filovirus- and Bornavirus-related sequences in 19 vertebrate genomes.
Decode-Led Study Suggests Kidney Disease Risk Variant Influences Other Age-Related Processes
Researchers from Decode Genetics and elsewhere reported that a genetic variant tied to chronic kidney disease may influence individuals' response to related diseases and environmental stressors in this population over time.
NIH to Fund NeuroAIDS Genetics
NIMH and NINDS will grant up to $6 million next year to start research into genes involved in neurocognitive disorders linked to HIV-1 and anti-retroviral treatments.
In Brief This Week: GE Healthcare; BioServe; DNA Genotek
In Brief This Week is a Friday column containing news items that our readers may have missed during the week.
Idaho Technology Licenses PCR Technology to DuPont
The deal covers reagents and methods using Idaho Tech's Sybr Green I technology and post-PCR melting curve analysis.
Vicent Forlenza is COO at Becton Dickinson, who named Christopher Jones to its board, and more.
Gen-Probe Posts Double-Digit Q2 Revenue Growth
The firm cited its Aptima Combo 2 assay for detecting chlamydia and gonorrhea, as well as products sold by Prodesse, as key revenue drivers.
Pathwork Diagnostics, Novartis Team Up for Cancer Biomarker Discovery
The biomarkers will be used to develop diagnostics for a range of cancer types.
AMP Members Concerned About NIH's Planned Genetic Test Registry
In comments to the NIH about the registry, the Association for Molecular Pathology said that in a survey among its members, less than 60 percent said they were willing to provide analytical and clinical validation information to the registry, and members worry about how the registry would be used by competitors, payors, and regulators.
Study: Lack of Correlation Between Messenger RNA, Protein Product Levels in Single E. Coli Cells
A single molecule imaging study suggests the levels of messenger RNA and protein produced from the same gene do not correlate with one another in individual Escherichia coli cells.
ISB Mum on Permit for Renovations to Former Merck Rosetta Research Center Building
The institute declined to comment on a permit it has been granted to renovate a building that formerly housed the Merck Rosetta Research Center building in Seattle.
Rheonix Plans FDA Submission for Warfarin Sensitivity Test
The firm intends to file for FDA clearance of the test, which would run on its CARD molecular diagnostics system.