Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
Jackson Lab Withdraws Request for $50M in State Funds for Controversial Florida Campus
January 05, 2011
Jackson Lab insisted in a statement that it intends to proceed with the project, explaining that despite the withdrawal it "will work with newly elected Florida Gov. Rick Scott to align the project with his goals for growing the state's economy."
Full-text access for registered users only.
Existing users login here.
New to GenomeWeb? Register quickly here for free access.
New to GenomeWeb? Register quickly here for free access.