Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Invitrogen Inks Cancer Dx Pact with Signalomics; Welcomes Competition from Emerging Rivals
Invitrogen has a variety of tools and technologies that it has acquired over the past couple of years that it believes can be employed in the roughly $2 billion molecular diagnostics space. Included among those technologies are assets, which are being used in the collaboration with Signalomics, gained through the acquisition of BioCrystal s BioPixels unit in October 2005. Subscribers: click headline for more
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