Sequencing and Analysis of the Hydra Genome
Chapman, Kirkness et al., Nature
An international research collaboration reports their sequencing and analysis of the Hydra magnipapillata genome, and compare it to the genomes of several other organisms. "The Hydra genome has been shaped by bursts of transposable element expansion, horizontal gene transfer, trans-splicing, and simplification of gene structure and gene content that parallel simplification of the Hydra life cycle," the authors write. They team suggests that comparisons of the Hydra genome to the reported sequences of other animals have helped them to elucidate the evolution of several of the organism's characteristics.
UCSD Team Frees Protein Identification From Database Searching Via 'Spectral Networks'
The UCSD approach does away with the database-searching step altogether by relying on the concept of spectral pairs: sets of spectra that occur naturally in most mass spec experiments as the result of overlapping peptides or from modified and unmodified versions of the same peptide.
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