Regulation and Function of miR-218 in Gastric Cancer Metastasis
Tie, Pan et al., PLoS Genetics
Researchers describe a negative feedback system between Robo1, a Slit receptor, and miR-218, wherein “decreased miR-218 levels eliminate Robo1 repression, which activates the Slit-Robo1 pathway through the interaction between Robo1 and Slit2, thus triggering tumor metastasis.” The authors suggest that the restoration of miR-218 supresses Robo1 espression and inhibits tumor cell invasion.
OME’s Commercial Arm Glencoe to Sell Licenses for Open-Source Bio-Formats Library
Glencoe and the Laboratory for Optical and Computational Instrumentation at the University of Wisconsin at Madison, the developer of Bio-Formats, said that the licensing deal will keep the software open source while allowing commercial organizations to redistribute it.
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