Family-Based Whole-Genome Sequencing Reveals Candidates for Mendelian Disease
Roach, Glusman et al., Science
Researchers at the Institute for Systems Biology and Complete Genomics have identified candidate disease-causing genes for Miller syndrome and ciliary dyskinesia, both Mendelian disorders. They sequenced the genomes of a family of four, allowing them to determine recombination sites with precision (at 99.999 percent accuracy) and identify rare single-nucleotide polymorphisms. "Our results demonstrate the unique value of complete genome sequencing in families," the authors write.
Life Tech Says Most SQL*LIMS Employees Expected to Transfer to LabVantage Following Sale of Business
"While the LIMS business is an important asset for a segment of our customers, it was not a perfect fit with our strategic direction," Mark Stevenson, Life Technologies' president and COO, said in a statement.
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