PTB Proteins Induce RNA Looping
Lamichhane, Daubner et al., PNAS
Researchers in the US and Switzerland report that polypyrimidine tract-binding proteins induce RNA looping ― a finding they deduced using FRET, NMR spectroscopy, and in vivo splicing data. They show that two PTB RNA recognition motifs can bind two distant pyrimidine tracts, bringing their 5' and 3' ends in close proximity, thus inducing loop formation.
Dutch Sequencing Service Shop to Bundle CLC Bio Software with Data
Under the terms of the agreement, BaseClear will provide all of its sequencing customers with a license for the company's CLC Genomics Workbench for assembly and downstream analysis of next-generation sequencing data.
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