Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Dassault-led European BioIntelligence Project to Modify Manufacturing IT Strategy for Life Sciences R&D
BioIntelligence, coordinated by French industrial firm Dassault Systèmes, will bring together pharma firms, software companies, and academic and government research labs to adapt product lifecycle management, or PLM, tools for use in the life sciences.
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