Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Complete Genomics Mulling Informatics, IT Options to Support $5K Genome Service
Complete Genomics has not yet announced the exact terms of its service, but the $5,000 price tag includes sequencing to 20-fold coverage and “the first few steps of analysis” such as alignment, assembly, and some automated annotation.
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