Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Agilent to Collaborate with UCSD on Network Visualization Software
Agilent's philanthropic arm, the Agilent Foundation, is sponsoring the project under Agilent's University Relations Program. The company said that the collaboration includes "scientific and financial support," but did not disclose funding details.
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