PTB Proteins Induce RNA Looping
Lamichhane, Daubner et al., PNAS
Researchers in the US and Switzerland report that polypyrimidine tract-binding proteins induce RNA looping ― a finding they deduced using FRET, NMR spectroscopy, and in vivo splicing data. They show that two PTB RNA recognition motifs can bind two distant pyrimidine tracts, bringing their 5' and 3' ends in close proximity, thus inducing loop formation.
Accelrys Reports 5 Percent Q3 Revenue Uptick
The company posted net income of $1 million for its fiscal third quarter compared to a net loss of $1.2 million in the year-ago period.
New to GenomeWeb? Register quickly here for free access.