Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Illumina Posts 31 Percent Q2 Revenue Growth; Acquires PCR Instruments Firm
Illumina's revenues rose sharply on rapid uptake of its HiSeq system. The firm also acquired Helixis for up to $105 million, providing it with a new, low-cost, real-time PCR system for genetic analysis.
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