Sequencing and Analysis of the Hydra Genome
Chapman, Kirkness et al., Nature
An international research collaboration reports their sequencing and analysis of the Hydra magnipapillata genome, and compare it to the genomes of several other organisms. "The Hydra genome has been shaped by bursts of transposable element expansion, horizontal gene transfer, trans-splicing, and simplification of gene structure and gene content that parallel simplification of the Hydra life cycle," the authors write. They team suggests that comparisons of the Hydra genome to the reported sequences of other animals have helped them to elucidate the evolution of several of the organism's characteristics.
German, American Team Confirms CYP2D6 Influence on Tamoxifen Response
October 07, 2009
Using a retrospective study involving more than 1,300 women with breast cancer, a group of researchers from Germany and the US found that individuals carrying poorer metabolizing versions of the CYP2D6 enzyme had increased rates of cancer recurrence.
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