Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
Emory, MCG Collaboration Wins $7.6M from NASA
November 12, 2010
Researchers from Emory University's Winship Cancer Institute and the Medical College of Georgia will study whether the risk of lung cancer is amplified by the stress response touched off by damage to DNA from exposure to HZE particles.
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