Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
UPDATE: Warfarin Genetic Testing Decreases Hospitalization Rate, Study Finds
March 16, 2010
Research presented at the American College of Cardiology scientific session in Atlanta today suggests individuals who receive genetic testing early in their warfarin treatment are up to 31 percent less likely to be hospitalized than those who don't.
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