Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
UC Berkeley Halts Genetic Testing Program, but Touts Opportunity for Ethical Debate
"Most of the benefit of this program has already been had," said a UC Berkeley genetics professor after the California Department of Public Health limited the scope of the university's educational genetic testing project because it determined it was providing medical information.
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