Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
UC Berkeley Fends off DTC Genomics Critics; Other Schools Mull Genetic Tests as Educational Tools
Despite criticism, UC Berkeley shows no signs of halting its proposed plans to genetically test incoming freshman this fall. Although UC Berkeley is the first to attempt to roll out genetic testing within its student body, other campuses around the country are planning similar projects.
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