Connection Between Epigenome, Selective Mutability, Evolution, and Human Disease
Li, Harris et al., PLoS Genetics
Researchers at the Baylor College of Medicine and elsewhere propose a "connection between the epigenome, selective mutability, evolution, and human disease" based on the findings of their study on associations of structural mutability with germline DNA methylation and with non-allelic homologous recombination mediated by low-copy repeats. "Combined evidence from four human sperm methylome maps, human genome evolution, structural polymorphisms in the human population, and previous genomic and disease studies consistently points to a strong association of germline hypomethylation and genomic instability," the Baylor-led team writes.
Study Finds Docs Could Face Greater Malpractice Risk in Personalized Rx Era
June 29, 2011
"Courts are willing to require the use and understanding of genetic information even before the medical community itself is ready and able to do so," according to researchers from Arizona State University who are tracking increasing liability risk for doctors within the context of genomic medicine.
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