Human Genetic Variation Alters Anthrax Toxin Sensitivity
Martchenko, Candille et al., PNAS
Researchers at Stanford University School of Medicine show that genetic variation affecting capillary morphogenesis gene 2, or CMG2, dramatically alters toxin sensitivity in humans. In its analysis, the team reports on "a CMG2 single-nucleotide polymorphism occurring frequently in African and European populations [that they found] independently altered toxin uptake." The group goes on to suggest "testing of genomically characterized human cell populations may offer a broadly useful strategy for elucidating effects of genetic variation on infectious disease susceptibility."
Sequenom Hires PDI to Launch and Sell Prenatal Test
Sequenom President and CEO Harry Stylli had previously said that the firm would work with a contract sales force organization and target a sales force of 150 to 175 reps focused on the obstetrics/gynecology market in the US.
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